Cardiopeptase is LifeLink’s brand of serrapeptase — a substance extracted from the microorganism Serratia sp.E15. Serrapeptase is a ‘protease’ enzyme — that is, it is a protein that destroys certain other kinds of proteins by chopping them into pieces.

Serrapeptase was discovered in the 1960s by Japanese researchers who were studying silkworms.1 Silkworms spin silk into cocoons, which protect them while they transform into adult insects: silkmoths. When the transformation is complete, the moths escape by dissolving holes in the cocoon’s silk. They do this by making use of the Serratia bacteria that live in the insects’ digestive tracts and which make serrapeptase.

The early investigators of serrapeptase realized its potential as an agent for clearing fibrous deposits in the body. They soon discovered that it also has anti-inflammatory properties1 and that it improves the tissue penetration of antibiotics.2 During the next two decades it became widely used clinically in Europe and Asia.3 Its reputation eventually worked its way to the United States where it is now increasingly used as a supplement and treatment for various conditions.

What we can’t tell you

In the U.S. and some other industrialized countries, government agencies like the U.S. Food and Drug Administration have adopted censorship as a method for intensifying their control over the supplement industry and its customers. Thus, FDA regulations prohibit us from telling you that any of our products are effective as medical treatments, even if they are, in fact, effective.

Accordingly, we will limit our discussion of CardioPeptase™ to a brief summary of relevant research, and let you draw your own conclusions about what medical conditions it may be effective in treating.

Serrapeptase has found a variety of usages based, presumably, on its ability to destroy specific kinds of proteins. These usages include:

  • Hastening recovery from acute or chronic ear, nose or throat disorders.4
  • Reducing symptoms of coughing in patients with “chronic airway disease”.3
  • Treating chronic pulmonary disease.5
  • Reducing swelling and pain after sprains and torn ligaments.6
  • Reducing swelling and pain after surgery.7,8,9,10
  • Dissolving blood clots and arterial plaques20
  • Improving penetraton of antibiotics in inflamed or infected tissues.11,12
  • Treating carpal tunnel syndrome.13
  • Enhancing the ability of antibiotics to prevent infections after implant surgery.14
  • Treating breast engorgement15 (a condition during breastfeeding that occurs when more milk accumulates in the breasts than the infant consumes).
  • Reducing the ability of food-poisoning bacteria to infect human tissues.16
Cardiovascular applications

Serrapeptase has aroused a great deal of interest as an agent for preventing or treating cardiovascular disease — in particular, atherosclerosis (‘hardening of the arteries’). According to current thinking on this subject, plaques form where artery walls have been injured by the immune system. The plaques accumulate debris from dead immune cells, fatty materials, and fibrous proteins like fibrin, elastin, and collagen.19 The plaques are held together by the fibrous proteins; serrapeptase can destroy fibrous proteins; therefore, it should come as no surprise to find that serrapeptase weakens arterial plaques and helps them to dissipate.


It was once widely believed in medical circles that proteins like serrapeptase cannot possibly be effective when used orally because they would be destroyed by acids in the stomach and therefore could not reach the tissues where they are needed. This has turned out to be false — studies have shown that serrapeptase and certain other enzymes can pass through the stomach intact and stlll be active after being absorbed into the blood.17

Low toxicity

One of the reasons for the increasing popularity of serrapeptase as an anti-inflammatory and pain reliever is that, unlike aspirin and many other anti-inflammatories, serrapeptase does not cause ulcers or stomach bleeding. Its toxicity is extremely low18 and (unlike most other anti-inflammatories) it rarely causes unwanted side effects.


Are CardioPeptase™ supplements useful for the conditions and purposes mentioned above? We aren’t allowed to tell you, so you should take a look at some of the references cited here, and then decide for yourself.

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